Table S1.

Institutional review boards at participating study sites

Site information		Name of institutional review board
	Prefecture
1	Hokkaido	National Hospital Organization Central Review Board
2	Ibaraki	National Hospital Organization Central Review Board
3	Ibaraki	Tsuchiura Kyodo General Hospital IRB
4	Ibaraki	Ibaraki Prefectural Central Hospital IRB
5	Ibaraki	Review Board of Human Rights and Ethics for Clinical Studies IRB
6	Tokyo	Tokyo-Eki Center-building Clinic IRB
7	Tokyo	Suzuki Clinic Internal Medicine and Cardiology IRB
8	Tokyo	Showa General Hospital IRB
9	Kanagawa	Yasuda Hospital IRB
10	Kanagawa	Sugiura Clinic IRB
11	Niigata	Niigata Rinko Hospital IRB
12	Niigata	Niigata City General Hospital IRB
13	Niigata	National Hospital Organization Central Review Board
14	Shizuoka	Review Board of Human Rights and Ethics for Clinical Studies IRB
15	Kyoto	Japanese Red Cross Kyoto Daini Hospital IRB
16	Kyoto	National Hospital Organization Central Review Board
17	Osaka	Chuto Hospital IRB
18	Osaka	National Hospital Organization Central Review Board
19	Nara	Nara Hospital Kinki University Faculty of Medicine IRB
20	Hyogo	Terada Clinic Internal Respiratory Medicine IRB
21	Hiroshima	National Hospital Organization Central Review Board
22	Hiroshima	Kure Kyosai Hospital-Hiroshima IRB
23	Hiroshima	Chugoku Central Hospital-Hiroshima IRB
24	Yamaguchi	National Hospital Organization Central Review Board
25	Kagawa	Yasuda Hospital IRB
26	Kagawa	KKR Takamatsu Hospital IRB
27	Kagawa	Takamatsu Municipal Hospital IRB
28	Kochi	Sugiura Clinic IRB
29	Fukuoka	Fukuoka University Hospital IRB
30	Fukuoka	Sugiura Clinic IRB
31	Saga	Saga-Ken Medical Center Koseikan IRB
32	Okinawa	Chuto Hospital IRB
33	Okinawa	Chuto Hospital IRB
34	Okinawa	Okinawa Prefectural Chubu Hospital IRB
35	Ibaraki	Ibaraki Higashi National Hospital IRB
36	Osaka	AMC Nishi-umeda Clinic IRB
37	Tokyo	AMC Nishi-umeda Clinic IRB
38	Osaka	Clinical Research Tokyo Hospital IRB
39	Hiroshima	Hiroshima Prefectural Hospital IRB

Abbreviation: IRB, institutional review board.