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. Author manuscript; available in PMC: 2019 Sep 14.
Published in final edited form as: J Mol Biol. 2018 Jun 18;430(18 Pt A):2951–2973. doi: 10.1016/j.jmb.2018.06.017

Figure 1. Characterization of the interaction PIPs of CFTR variants.

Figure 1

A. (Upper) Immunoblot analysis of CFTR and tubulin from a lysate prepared from CFBE41o- null cells transduced with the indicated CFTR variant. (Lower) Immunoblot analysis CFTR immunoprecipitation of samples shown in A (upper). B. Heat map of the Jaccard similarity indices for the indicated pairwise comparisons. C. Heat map of bait normalized protein recovery in the immunoprecipitation of the indicated CFTR variant. The data is presented as a log2 of the additive peptide intensity normalized to the additive CFTR peptide intensity and sorted from most to least abundant based on recovery with WT-CFTR.

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