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. Author manuscript; available in PMC: 2019 Sep 14.
Published in final edited form as: J Mol Biol. 2018 Jun 18;430(18 Pt A):2951–2973. doi: 10.1016/j.jmb.2018.06.017

Figure 2. The differential interaction PIPs of Class II CFTR variants identifies targets for correction of F508del-CFTR.

Figure 2

A. Venn diagram comparing the total protein content of the PIPs of the indicated CFTR variants. B. Venn diagram comparing the protein content of the PIPs of the indicated CFTR variants for proteins that exhibit a statistically significant difference in binding affinity relative to WT-CFTR. C. Venn diagram comparing the protein content of the PIPs of the indicated CFTR variants for proteins that exhibit a statistically significant increase in binding affinity relative to WT-CFTR. D. Venn diagram comparing the protein content of the PIPs of the indicated CFTR variants for proteins that exhibit a statistically significant decrease in binding affinity relative to WT-CFTR.

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