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Twenty-two group D chimeric mice were sacrificed at weeks at 2 (n=3), 4 (n=4), 6 (n=4), 8 (n=4), 10 (n=2), and 13 (n=5) weeks after HBV inoculation. Real-time qPCR was performed to measure the level of serum HBV DNA and total intrahepatic HBV DNA.
