Table 3.

Features and algorithms used in multiple-feature integrative methods.

	Feature	Ben-Hur et al. a	Miller et al. b	Qi et al. c	Scott et al. d	Xu et al. e	PAIR f	PrePPI g	FpClass h	STRI-NG i	Taghi-pour et al. j	# of times used
Sequence	MOT/DOM	X		X	X	X	X		X			6
	NGM	X										1
	PCH								X			1
	HOM	X		X	X	X	X		X	X		7
	COD		X									1
	PHP			X		X	X	X		X		5
	FUS			X		X				X		3
	GNB			X		X				X		3
	PTM				X				X			2
Function	GO	X	X	X		X	X	X	X		X	8
	MIPS							X				1
Experiment	COX		X	X	X	X	X	X	X	X	X	9
	XPI		X	X								2
	CLA			X								1
	ESN		X	X				X				3
	LOC		X		X		X					3
	COR										X	1
	SNL			X								1
	MUT			X								1
Structure	STR							X				1
	DIS				X							1
Network	NET	X	X		X				X		X	5
Literature	TXT									X		1
Integrating method		LPK	SVM	RF, KNN, NB, DT, LR, SVM	NB	NB	SVM	NB	NOR	LNR	NB, MCL

References of each method:

^a(Ben-Hur & Noble, 2005);

^b(Miller et al., 2005);

^c(Qi et al., 2006);

^d(Scott & Barton, 2007);

^e(Xu et al., 2010);

^f(M. Lin, Shen, & Chen, 2011);

^g(Q. C. Zhang et al., 2012);

^h(Kotlyar et al., 2015);

ⁱ(D. Szklarczyk et al., 2017);

^j(Taghipour et al., 2017)