Fig. 2.
Validation of model to data from systematic reviews. Data are shown as points and model predictions as solid lines. a Relationship between PvPRLM and clinical incidence based on data reviewed by Battle et al.30. Studies included in this review came from throughout the world, had various age ranges, and differences in the frequency of active case detection (ACD) for clinical cases of P. vivax. b Relationship between EIR and PvPRLM compared to data reviewed by Battle et al. plus data from a study in Papua New Guinea by Burkot et al.60. Orange points denote studies where infectious mosquitoes were confirmed as P. vivax positive, and green points denote studies where mosquitoes were identified as infectious but without Plasmodium species identification. In some studies, a range was provided instead of a point estimate. c Relationship between PvPRLM and PvPRPCR compared to data reviewed by Moreira et al.31. Data are from throughout the world and are based on studies with various age ranges. d Model-predicted relationship between PvPRLM and hypnozoite prevalence. As it is currently not possible to directly detect hypnozoites, this relationship cannot be formally compared to any data