Table 1.
Correlation table, showing the relationships between questionnaires, disease severity and levodopa – equivalent doses (upper panel) and between fatigue (PFS), depression (BDI), sleep disturbance (PDSS2), disease severity (MDS-UPDRS total) and LC/SN degeneration (lower panel).
| *BF10 > 5, **BF10 > 10, ***BF10 > 50 | Depression (BDI) |
Sleep (PDSS2) |
Disease (MDS-UPDRS) |
Medication(LED) | |
|---|---|---|---|---|---|
| Fatigue (PFS) | Kendall’s tau | 0.401*** | 0.318* | 0.223 | 0.125 |
| BF10 | 77.35 | 8.674 | 1.072 | 0.37 | |
| p-value | < 0.001 | 0.007 | 0.077 | 0.331 | |
| Depression (BDI) | Kendall’s tau | 0.248 | 0.267 | 0.089 | |
| BF10 | — | 1.923 | 1.966 | 0.293 | |
| p-value | 0.04 | 0.039 | 0.494 | ||
| Sleep (PDSS2) | Kendall’s tau | 0.24 | 0.136 | ||
| BF10 | — | 1.371 | 0.406 | ||
| p-value | 0.059 | 0.29 | |||
| Disease (MDS-UPDRS) | Kendall’s tau | 0.323 | |||
| BF10 | — | 4.405 | |||
| p-value | 0.015 | ||||
| *BF10 > 5, **BF10 > 10, ***BF10 > 50 | Fatigue (PFS) | Depression (BDI) | Sleep (PDSS2) | Disease (MDS-UPDRS) | |
| Locus Coeruleus | Kendall’s tau | 0.061 | −0.306* | 0.171 | −0.085 |
| BF10 | 0.248 | 5.104 | 0.588 | 0.291 | |
| p-value | 0.609 | 0.012 | 0.161 | 0.509 | |
| Substantia Nigra | Kendall’s tau | −0.281 | −0.139 | −0.018 | −0.039 |
| BF10 | 3.35 | 0.421 | 0.224 | 0.264 | |
| p-value | 0.018 | 0.258 | 0.882 | 0.762 | |
The BF10 represents the relative probability of the data under alternative hypothesis H1 with respect to null hypothesis H0 (i.e. BF10 of 20 indicates that the data is 20 times more likely to be observed under the alternative hypothesis).