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. 2018 Aug 17;8:12412. doi: 10.1038/s41598-018-30882-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of AUS0004 (wild-type strains) and the deletion mutants in a mouse model of urinary tract infection. Groups of 10 BALB/c female mice were transurethral challenged with approximately 1 × 10⁸ cells of the indicated strains. Data are expressed as the log₁₀ colony-forming units (CFUs)/g of bacteria recovered from kidney and urinary bladder homogenates four days after the challenge. The log₁₀ CFUs of both kidneys were combined and averaged. A value of 0 was assigned to the uninfected organs. Horizontal bars represent geometric means. Log₁₀ counts were compared for statistical significance by two-way ANOVA. P values < 0.05 were considered significant. ^*<0.05, ^**<0.005, ^***<0.001.