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. 2018 Aug 17;8:12307. doi: 10.1038/s41598-018-29968-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Rat TA muscle defect model. (A) Tetanic force (N · mm/kg) and (B) TA muscle weight (% of contralateral normal TA muscle) were measured at 4 and 8 weeks after implantation (n = 3 per group, triple measures per sample). Tetanic force and muscle weight of bioprinted muscle constructs-implanted group had significantly increased when compared with other groups (*P < 0.05 compared with non-treated group at 4 weeks, **P < 0.05 compared with non-treated, gel only, and non-printed groups at 4 weeks, and ^†P < 0.05 compared with non-treated, gel only, and non-printed groups at 8 weeks).