Table 1.

Session schedule

Time (min)	Event
−75	Urine toxicology, breathalyzer, carbon monoxide, breakfast
−60	Pain assessments, BP/HR, pupil measurement, SE-VAS
−45	Capsule administration
	(0.0, 2.5 or 5.0 mg oxycodone, oral)
−20	Pain assessments, BP/HR, pupil measurement, capsule-RF, SE-VAS
0	Cannabis administration
	(0 or 5.6%, smoked)
15	BP/HR, pupil measurement, capsule-RF, cannabis-RF, SE-VAS
30	Pain assessments, BP/HR, capsule-RF, cannabis-RF, SE-VAS,
60	Pain assessments, BP/HR, pupil, capsule-RF, cannabis-RF, SE-VAS,
90	Pain assessments, BP/HR, pupil, capsule-RF, cannabis-RF, SE-VAS,
120	Pain assessments, BP/HR, capsule-RF, cannabis-RF, SE-VAS
150	BP/HR, lunch
180	Pain assessments, BP/HR, pupil, capsule-RF, cannabis-RF, SE-VAS
195	Choice to purchase 1-3 puffs of marijuana followed by smoking
225	BP/HR, SE-VAS
255	BP/HR, SE-VAS
285	BP/HR, SE-VAS
300	BP/HR, Field Sobriety Test, participant discharge

Timing of session events relative to cannabis smoking. Session began at approximately 9 AM

Pain assessments Cold Pressor Test, McGill Pain Questionnaire, and Painful and Bothersome Rating Forms, BP/HR blood pressure and heart rate readings, SE-VAS Subjective Effects -Visual Analog Scale, Capsule-RF Capsule Rating Form, Cannabis-RFC Cannabis Rating Form