Table 3.
Pain ratings
Drug condition | Oxycodone | 0.0 mg | 0.0 mg | 2.5 mg | 2.5 mg | 5.0 mg | 5.0 mg |
Cannabis | 0.0 % | 5.6 % | 0.0 % | 5.6 % | 0.0 % | 5.6 % | |
Subjective effect | MPQ | 2.2 ± 0.5 | 1.5 ± 0.5 | 2.0 ± 0.5 | 0.7 ± 0.6 | 1.7 ± 0.4 | 1.2 ± 0.4 |
Painfulness | 0.4 ± 0.1 | 0.6 ± 0.1 | 0.6 ± 0.1 | 0.3 ± 0.2 | 0.3 ± 0.1 | 0.2 ± 0.1 | |
Bothersomeness | 0.6 ± 0.1 | 0.6 ± 0.2 | 0.8 ± 0.2 | 0.6 ± 0.2 | 0.5 ± 0.2 | 0.0 ± 0.2 |
Mean reductions from baseline in pain ratings ± standard error of the mean (SEM) for the McGill Pain Questionnaire (MPQ), and Painfulness and Bothersomeness scales after administration of placebo (inactive cannabis + 0 mg oxycodone), oxycodone (2.5 and 5.0 mg) and active cannabis (0.0 and 5.6% THC) administered alone or together