Table 1.
Characteristics of the novel replication patients.
| Characteristic | 24-hour AER | nu-AER | P |
|---|---|---|---|
| N | 902 | 357 | |
| Men (%) | 457 (50.7) | 176 (49.3) | NS |
| Age at onset of diabetes (years) | 16.7 ± 9.5 | 14.9 ± 8.9 | 0.001 |
| Age (years) | 38.2 ± 12.3 | 42.1 ± 12.6 | <0.001 |
| Duration of diabetes (years) | 21.5 ± 11.0 | 27.2 ± 12.1 | <0.001 |
| AHT medication (%) | 288 (31.9) | 183 (51.3) | <0.001 |
| SBP (mmHg) | 132.6 ± 17.3 | 136.1 ± 17.8 | 0.0025 |
| DBP (mmHg) | 78.9 ± 9.6 | 78.0 ± 10.4 | NS |
| HbA1c (%) | 8.5 ± 1.4 | 8.5 ± 1.4 | NS |
| HbA1c (mmol/mol) | 69.3 ± 15.0 | 69.1 ± 15.2 | NS |
| Mean HbA1c (%) | 8.5 ± 1.3 | 8.5 ± 1.2 | NS |
| Mean HbA1c (mmol/mol) | 69.6 ± 13.9 | 69.3 ± 13.6 | NS |
| Number of HbA1c measurements | 8 (2, 18) | 15 (6, 31) | <0.001 |
| Retinal laser treatment (%) | 20.8% | 35.2% | <0.001 |
| 24 h AER (mg/24 h), mean ± SD | 119 ± 523 | ||
| 24 h AER (mg/24 h), median (IQR) | 9 (5, 26) | ||
| nu-AER (μg/min), mean ± SD | 114 ± 698 | ||
| nu-AER (μg/min), median (IQR) | 8 (3, 24) |
Characteristics were collected at the same visit as the 24-hour/nu-AER. Mean HbA1c refers to mean of all available HbA1c since the onset of diabetes. Data are given as numbers (percent), or mean ± standard deviation (SD), or medians (interquartile range [IQR]). AHT: anti-hypertensive. SBP: systolic blood pressure; DBP: diastolic blood pressure. P: difference between the replication sets; p-values > 0.05 are indicated as non-significant (NS); calculated with Welch two sample t-test for continuous variables, and Pearson’s Chi-squared test for binary variables.