Fig. 1.

Overview of study design and analysis. Clinical assessments occurred at baseline and the allergic subjects were re-assessed several years later at follow-up, at which point 59% had resolved allergy. Bloods were collected at both time points, and frozen for later analysis. Experiments were batched such that naive CD4+ T cells (baseline and follow-up) were flow sorted from bloods prior to cell culture and molecular analyses. NA non-allergic, FA food allergy