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. 2018 Aug 17;8:12332. doi: 10.1038/s41598-018-30753-7

Table 3.

Overrepresented signaling pathways of DOCK8 interacting proteins in PBL of ERU cases.

Signaling pathway p-value No. of proteins observed List of observed proteins (gene symbols)
ARP2 Actin Related Protein 2 Homolog (Yeast) 8,39E-06 6 VCL, ARPC4, CAPZA1, ACTR3, GSN, ACTB
Integrin 3,87E-04 12 LGALS3BP, ITGB3, VCL, FLNA, FN1, C3, TRF, VWF, ACTN1, TLN1, ILK, C1QA
Cofilin 1,44E-03 8 MYO9B, HSPB1, SEPT7, NEXN, PHB, GSN, SEPT2, ACTB

List of the top 3 significantly (p-value) enriched signaling pathways containing DOCK8-interacting proteins enriched in ERU PBL (≥2 peptide counts; enrichment factor ≥4) analyzed by Genomatix (version 3.7).