Table 6.
Group | Treatment (Dose) | Uterine weight (mg/100 g body weight; mean ± S.D) | Vaginal cornification |
---|---|---|---|
1 | Control | 70.24 ± 5.35a | NIL |
2 | Ethinyl Estradiol (1 µg/rat per day) | 335.40 ± 7.56a | +++ |
3 | APB (500 mg/kg) | 102.65 ± 7.43c | + to ++ |
4 | Ethinyl estradiol (1 µg/rat per day) +APB (500 mg/kg) | 410.67 ± 9.09 a | +++ |
5 | Ethinyl estradiol (1 µg/rat per day) +WPB (500 mg/kg) | 408.58 ± 8.27 | +++ |
Values are expressed as mean ± S.D.
P values a = P < 0.05, b = P < 0.01, c = P < 0.001 when compared with normal control + : Nucleated Epithelial Cells, + +: Nucleated Epithelial Cells and Cornified Cells, +++: Cornified cells.