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. 2018 Aug 14;15:97–102. doi: 10.1016/j.bbrep.2018.08.001

Table 6.

Effect of Extracts on Estrogenic and Anti-Estrogenic Study.

Group Treatment (Dose) Uterine weight (mg/100 g body weight; mean ± S.D) Vaginal cornification
1 Control 70.24 ± 5.35a NIL
2 Ethinyl Estradiol (1 µg/rat per day) 335.40 ± 7.56a +++
3 APB (500 mg/kg) 102.65 ± 7.43c + to ++
4 Ethinyl estradiol (1 µg/rat per day) +APB (500 mg/kg) 410.67 ± 9.09 a +++
5 Ethinyl estradiol (1 µg/rat per day) +WPB (500 mg/kg) 408.58 ± 8.27 +++

Values are expressed as mean ± S.D.

P values a = P < 0.05, b = P < 0.01, c = P < 0.001 when compared with normal control + : Nucleated Epithelial Cells, + +: Nucleated Epithelial Cells and Cornified Cells, +++: Cornified cells.