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. 2018 Jul 19;159(9):3235–3244. doi: 10.1210/en.2018-00451

Figure 6.

Figure 6.

Olfm4 deletion decreases insulin resistance and increases GSIS in HFD-fed mice. Male WT (n = 10) and Olfm4-deficient mice (n = 11) were fed an HFD for 2 months. (A) Body weight of WT and Olfm4-deficient mice. (B) Blood glucose levels in WT and Olfm4-deficient mice after 16-h overnight fasting. (C) Plasma insulin levels in WT and Olfm4-deficient mice after 16-h overnight fasting. (D) HOMA-IR index in WT and Olfm4-deficient mice. (E) Blood glucose levels during GTTs for WT and Olfm4-deficient mice. (F) AUC for (E). (G) Plasma insulin levels during GTTs for WT and Olfm4-deficient mice. (H) Fold increase (over baseline, 0 min) in insulin levels at 15 min in WT and Olfm4-deficient mice. (I) Blood glucose levels during ITTs for WT and Olfm4-deficient mice. Data are expressed as mean ± SD. *P < 0.05 when compared with WT.