Table 2.
The correlation between cognitive performance and connectivity strength of each region of interest (ROI) in the sensorimotor network (SMN) and salience network (SAL) before carotid artery stenting.
| MMSE | MoCA | CVLT_Total | TMT-A | Stroop_W Inc | Stroop_W Effect | Stroop_C Inc | Stroop_C Effect | |
|---|---|---|---|---|---|---|---|---|
| Hyper-connectivity ROI in SMN | ||||||||
| Pallidum, R | −0.32 | −0.25 | −0.59⁎, † | 0.28 | 0.33 | 0.18 | 0.43⁎ | −0.03 |
| Putamen, L | 0.02 | −0.07 | −0.35 | 0.04 | 0.06 | 0.01 | 0.43⁎ | 0.14 |
| Caudate, L | 0.14 | −0.19 | −0.29 | 0.19 | 0.22 | 0.08 | 0.48⁎, † | 0.26 |
| Premotor, L | −0.13 | 0.06 | −0.45⁎ | 0.03 | 0.28 | 0.34 | 0.1 | −0.18 |
| Thalamus, L | 0.05 | −0.13 | −0.11 | 0.1 | −0.03 | −0.07 | 0.62⁎, † | 0.41† |
| Hypo-connectivity ROI in SMN | ||||||||
| Premotor, R | 0.24 | 0.13 | 0.02 | −0.1 | −0.08 | −0.09 | −0.46⁎ | −0.32 |
| Occipital_Sup, R | 0.14 | 0.08 | 0.39 | −0.18 | −0.34 | −0.66⁎, † | −0.2 | 0.06 |
| Precuneus, R | 0.08 | −0.01 | 0.25 | −0.09 | −0.27 | −0.37 | −0.54⁎, † | −0.29 |
| Hyper-connectivity ROI in SAL | ||||||||
| Prefrontal, BA 9, L | −0.25 | −0.08 | −0.22 | 0.15 | 0.47⁎, † | 0.54⁎, † | 0.16 | 0.02 |
| Prefrontal, BA 10, L | −0.27 | 0.16 | −0.14 | 0.15 | 0.45⁎, † | 0.54⁎, † | 0.34 | 0.15 |
| Inf. frontal, BA 45, L | 0.16 | −0.27† | −0.37 | 0 | 0.15 | 0.48⁎, † | 0.53⁎, † | 0.50⁎, † |
| Postcentral, R | 0.11 | −0.42 | −0.19 | 0.15 | 0.15 | 0.28 | 0.41 | 0.28 |
| Calcarine, R | −0.36 | −0.26 | 0.06 | 0.16 | 0.22 | 0.21 | 0.28 | 0.13 |
| Hypo-connectivity ROI in SAL | ||||||||
| Insula, L | 0.46⁎ | 0.2 | 0.29 | −0.53⁎, † | −0.58⁎, † | −0.59⁎, † | −0.44⁎ | −0.03 |
| Cingulum_Mid, R | 0.24 | 0.50⁎, † | 0.32 | −0.32 | −0.34 | −0.2 | 0.08 | 0.33 |
| Temporal_Mid, R | −0.07 | 0.21 | 0.14 | −0.04 | −0.08 | −0.02 | −0.16 | 0 |
| Premotor, R | 0.17 | 0.05 | 0.36 | −0.18 | −0.19 | −0.26 | −0.21 | 0.2 |
| Inf. Orb. frontal, BA 47, R | 0.24 | 0.1 | 0.03 | −0.09 | −0.06 | −0.12 | −0.06 | 0.15 |
| Hippocampus, R | 0.16 | −0.25 | 0.18 | −0.08 | −0.25 | −0.59⁎, † | −0.45⁎ | −0.2 |
| SupraMarginal, R | 0.16 | 0.2 | 0.25 | −0.27 | −0.21 | −0.19 | 0.01 | 0.33 |
MMSE indicates Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; TMT-A, Trail-Making Test A; CVLT_Total, California Verbal Learning Test total recall score; Stroop_W, word-naming Stroop test; Stroop_C, color-naming Stroop test; Con, congruent; Neu, neutral; Inc., incongruent; Inf, inferior; Orb, orbital.
⁎
p < .05 after adjusted for age and education.
†
p < .05 after adjusted for age, education, leukoaraiosis, and infarct severity on MRI.