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. 2018 Aug 1;29(8):886–901. doi: 10.1089/hum.2017.220

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Andrea Maddalena et al. 2018; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — High-throughput screening of 273 kinase inhibitors identifies 12 compounds that enhance adeno-associated viral (AAV) transduction. (A and B) Enhanced green fluorescent protein (eGFP)-positive cells/total cells: results from the analysis were organized and plotted in ascending value both in the chart (A) and in the table (B). The dashed line indicates the value obtained with the PI as positive control. (C and D) Mean fluorescence intensity in eGFP-positive cells normalized to the mean eGFP fluorescence intensity measured in the positive control (PI 7.5 μM): results from the analysis were organized and plotted in ascending value both in the chart (C) and in the table (D). PI, proteasome inhibitor (Calpain inhibitor 1); ID, identification number (according to the coordinates on the 384-well plate). Values are presented as the mean of three independent experiments.