Table 3.
Expression of LINC00996 and clinicopathological parameters in CRC obtained from TCGA
| Clinicopathological features | n | LINC00996 relative expression
|
t | P-value |
|---|---|---|---|---|
| Mean ± SD | ||||
| Tissue | −0.954 | <0.001 | ||
| Tumor | 456 | 23.8587±20.8016 | ||
| Normal | 41 | 88.0016±42.7183 | ||
| Age | 0.067 | 0.947 | ||
| <60 | 124 | 25.1532±25.1862 | ||
| ≥60 | 326 | 24.9601±28.01607 | ||
| Gender | −0.439 | 0.661 | ||
| Male | 237 | 25.5485±30.0389 | ||
| Female | 213 | 24.4178±23.7941 | ||
| Lymphatic invasion | 1.012 | 0.312 | ||
| Yes | 161 | 23.1553±22.8174 | ||
| No | 246 | 25.9309±29.4945 | ||
| AJCC pathologic T | F=0.103a | 0.902 | ||
| Tis | 1 | 37 | ||
| T1 | 11 | 25.9091±23.0150 | ||
| T2–T4 | 438 | 24.9635±27.3828 | ||
| AJCC pathologic N | 1.075 | 0.283 | ||
| N0 NX | 265 | 26.1660±28.3905 | ||
| N1–2 | 185 | 23.3622±25.4817 | ||
| AJCC pathologic M | 3.25 | 0.002 | ||
| M0 MX | 381 | 26.1234±28.1145 | ||
| M1 | 62 | 16.9839±19.0155 | ||
| Pathologic stage | 0.861 | 0.39 | ||
| I–II | 250 | 25.8720±28.2844 | ||
| III–IV | 191 | 23.6073±26.1344 |
Note:
a
One-way analysis of variance analysis was performed.
Abbreviations: AJCC, American Joint Committee on Cancer; TCGA, the Cancer Genome Atlas; CRC, colorectal cancer.