Table 5.
ICU and hospital mortality according to severity of ARDS using various definitions
| Definition | Severitya | Number of patients | ICU mortality (%) | Hospital mortality (%) |
|---|---|---|---|---|
| Berlin-CXR | No ARDS | 240 | 37 (15.4) | 62 (25.8) |
| Mild ARDS | 85 | 19 (22.4) | 31 (36.5) | |
| Moderate ARDS | 62 | 5 (8.1) | 16 (25.8) | |
| Severe ARDS | 69 | 18 (26.1) | 31 (44.9) | |
| Berlin-LUS | No ARDS | 227 | 27 (11.9) | 61 (26.9) |
| Mild ARDS | 92 | 24 (26.1) | 30 (32.6) | |
| Moderate ARDS | 73 | 10 (13.7) | 23 (31.5) | |
| Severe ARDS | 64 | 18 (28.1) | 26 (40.6) | |
| Berlin-CXR or Berlin-LUS | No ARDS | 161 | 20 (12.4) | 39 (24.2) |
| Mild ARDS | 120 | 28 (23.3) | 40 (33.3) | |
| Moderate ARDS | 93 | 11 (11.8) | 28 (30.1) | |
| Severe ARDS | 82 | 20 (24.4) | 33 (40.2) |
ARDS acute respiratory distress syndrome, CXR chest radiography, ICU intensive care unit, LUS lung ultrasound
aMild ARDS: ratio of arterial partial pressure of oxygen to inspired fraction of oxygen (P/F) 201–300 mmHg and positive end-expiratory pressure (PEEP)/continuous positive airway pressure (CPAP) ≥5 cmH2O using noninvasive ventilation (which may include CPAP or bi-level positive airway pressure) or invasive mechanical ventilation (IMV); moderate ARDS: P/F 101–200 mmHg and PEEP ≥ 5 cmH2O using IMV only; severe ARDS: P/F ≤ 100 mmHg and PEEP ≥ 5 cmH2O using IMV only