Table 2.

Association analysis of the rs2228570 and cases (stage II)

SNP	Group	Genotype OR (95% CI)a					Allele
		WT	Ht + MT	Additive	Dominant	Recessive	Major/Minor	OR (95% CI)	P-value
rs2228570		CC	TC + TT				C/T
	Control	902	1558+661	1.146 (1.053–1,247)	1.184 (1.018–1.376)	1.209 (1.064–1.374)	3362/2880	1.15 (1.05-1.25)	0.806c
	case	553	815 + 310	P = 0.002	P = 0.028	P = 0.004	1921/1435		0.002b

^a Adjusted for sex and age

^b P-value of χ² test for comparison of allele between case and control group

^c P-value of Fisher’s exact χ² test for HWE

WT wild type, Ht heterozygote, MT mutant type

OR Odds ratio

CI Confidence interval