Table 3.
Comparison of clinical features according to three pathological classifications in 74 adults with HSPN
| Factor | Age (years) | P values | eGFR (mL/min/1.73m2) | P values | Proteinuria (g/day) | P values |
|---|---|---|---|---|---|---|
| E0 | 47.4 ± 18.0 | 0.85 | 77.1 ± 29.2 | 0.83 | 0.77 [0.48–1.32] | < 0.001 |
| E1 | 48.2 ± 17.0 | 75.7 ± 22.4 | 1.83 [1.40–4.58] | |||
| S0 | 46.9 ± 18.1 | 0.65 | 77.2 ± 26.6 | 0.80 | 1.38 [0.78–2.44] | 0.74 |
| S1 | 48.7 ± 16.8 | 75.6 ± 25.4 | 1.41 [0.64–2.25] | |||
| T0 | 45.6 ± 17.3 | 0.048 | 82.5 ± 23.5 | < 0.001 | 1.41 [0.63–2.32] | 0.69 |
| T1 or 2 | 54.8 ± 16.3 | 57.3 ± 23.7 | 1.29 [0.74–2.44] | |||
| C0 | 44.6 ± 19.6 | 0.016 | 84.5 ± 30.1 | 0.098 | 0.60 [0.44–1.07] | < 0.001 |
| C1 | 44.7 ± 15.9 | 76.1 ± 23.5 | 1.50 [0.99–2.04] | |||
| C2 | 58.3 ± 13.7 | 66.6 ± 21.9 | 2.30 [1.70–4.89] | |||
| JHC I | 42.5 ± 17.7 | 0.005 | 85.5 ± 24.8 | < 0.001 | 1.10 [0.57–1.84] | 0.10 |
| JHC II or III | 53.7 ± 15.2 | 66.2 ± 23.2 | 1.70 [0.96–2.55] | |||
| ISKDC I or II | 43.8 ± 20.2 | 0.22 | 87.7 ± 28.5 | 0.020 | 0.67 [0.45–1.12] | 0.0052 |
| ISKDC III or IV | 49.3 ± 16.2 | 72.2 ± 23.6 | 1.70 [0.98–2.49] |
HSPN Henoch- Schönlein purpura nephritis, eGFR estimated glomerular filtration rate, E endocapillary proliferation, S segmental sclerosis/adhesion, T tubular atrophy/interstitial fibrosis, C cellular or fibrocellular crescents, JHC Japanese histologic classification, ISKDC International Study of Kidney Disease in Children