Table 2.
Baseline characteristics of study population
| Study Name | Fluid type | Age (years) | Gender | CKD | Baseline serum creatinine (mg/dl) | Sepsis and/or septic shock | MV | Vasopressor | ICU admission indication | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | Median (IQR) | Male | Female | Mean | Median | Medical | Surgical | ||||||
| Young [10] | Balanced | 60.1 (16.79) | – | 64% | 36% | – | 0.98 (0.76) | 4% | 67% | – | 29% | 71% | |
| Saline | 60.95 (16.25) | 67% | 34% | 0.99 (0.68) | 4% | 66% | 28% | 72% | |||||
| Verma [16] | Balanced | – | 62 (45–70) | 62% | 38% | – | – | 0.85 (0.58–1.34) | 46% | 58% | 46% | 58% | 42% |
| Saline | 64 (46–72) | 64% | 36% | 0.9 (0.6–1.21) | 41% | 56% | 32% | 48% | 52% | ||||
| Semler [15] | Balanced | – | 58 (44–69) | 57% | 43% | 17% | – | 0.89 (0.47–1.1) | 15% | 34% | 26% | 78% | 22% |
| Saline | 58 (44–69) | 58% | 42% | 17% | 0.89 (0.47–1.1) | 15% | 35% | 26% | 79% | 21% | |||
| Semler [11] | Balanced | – | 57 (44–68) | 52% | 48% | 23% | – | – | 25% | 34% | 22% | – | – |
| Saline | 58 (46–70) | 54% | 46% | 23% | 29% | 34% | 25% | ||||||
| Young [17] | Balanced | 38 (19) | – | 73% | 27% | – | – | – | – | – | – | – | – |
| Saline | 39 (14) | 79% | 21% | ||||||||||
| Ratanarat [18] | Balanced | – | – | – | – | – | – | – | – | – | – | – | – |
| Saline | |||||||||||||
CKD chronic kidney disease, MV mechanical ventilator, ICU intensive care unit, SD standard deviation, IQR interquartile range