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. 2018 Aug 17;15:56. doi: 10.1186/s12977-018-0440-3

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Growth of 5326 and 96USSN20 clinical isolates in escalating concentrations of dolutegravir (DTG), bictegravir (BIC), cabotegravir (CAB) and elvitegravir (EVG). The rise in drug concentrations were related to the acquisition of resistance mutations at the designated weeks of selection