Table 2.

Polymorphism analysis of inhibitory B-cell epitopes

Epitopea	Position (amino acid)	Epitope sequence (based on Sal-1)	S	Si	Pa	K	H	Hd ± SD	π ± SD	dN − dS	Taj D	D* (F&L)	F* (F&L)
H1	306–321	FHRDITFRKLYLKRKL	1	0	1	0.3	2	0.28 ± 0.077	0.00593 ± 0.001	0.007	0.31	0.55	0.56
H2	328–341	EGDLLLKLNNYRYN	0	0	0	0	0	0	0	0	0	0	0
H3	384–399	DEKAQQRRKQWWNESK	5	0	5	1.6	6	0.81 ± 0.020	0.0341 ± 0.002	1.99b	1.68	1.11	1.27
M1	344–355	FCKDIRWSLGDF	0	0	0	0	0	0	0	0	0	0	0
M2	414–429	LKGNFIWICKLNVAVN	2	0	2	0.6	3	0.401 ± 0.085	0.012 ± 0.002	1.36	0.48	0.48	0.76
M 3	432–447	PQIYRWIREWGRDYVS	2	0	2	0.5	4	0.452 ± 0.078	0.010 ± 0.002	0.02	0.17	0.76	0.68
L2	400–411	AQIWTAMMYSVK	0	0	0	0	0	0	0	0	0	0	0
L3	364–377	MEGIGYSKVVENNL	1	0	1	0.5	2	0.511 ± 0.019	0.011 ± 0.0004	1.1	1.68	0.55	1.01
L1	282–293	CIPDRRYQLCMK	0	0	0	0	0	0	0	0	0	0	0
L4	272–286	DWDCNTKKDVCIPD	0	0	0	0	0	0	0	0	0	0	0

^a[18]; ^b p < 0.02; S = number of variable (segregating) sites, Si = singleton variable sites, Pa = parsimony informative sites, K = average number of pair-wise nucleotide differences, H = number of haplotypes, Hd = haplotype diversity, SD = standard deviation, π = nucleotide diversity, dN = non synonymous substitution, dS = synonymous substitution, D⁄(F&L) = Fu and Li’s D⁄ test statistic, F⁄(F&L) = Fu and Li’s F⁄ test statistic. Bold and underline indicate polymorphic amino acid residues