Table 1.

The characteristics of the included studies

Author, Year, Location	Study Year	NOS	Age	Gender(Male)	SNPs	ONFH				Control				HWE
			ONFH/Control	ONFH/Control		N	WH	HT	MH	N	WH	HT	MH	Χ2*	P
Yin JM, [32] 2014, China	2001.11–2013.9	7	44.6 ± 11.3/44.7 ± 11.7	326/278	ApoA1-G75A(rs1799837)	429	215	73	141	368	170	114	84	43.758	< 0.001
					ApoB-EcoR I(rs1042031)	429	391	38	0	368	324	44	0	1.488	0.2226
					ApoB-Xba I(rs693)	429	394	35	0	368	327	41	0	1.281	0.2578
					ApoB-3′-VNTR	429	336	93	0	368	299	69	0	3.938	0.0583
Hirata T, [29] 2007, Japan	1983–2004	7	40.8(20–64)/ 36.1 (9–63)	22/91	ApoB-C7623T	33	27	6	0	122	115	6	1	2.755	0.0969
					ApoB-G12619A	34	33	1	0	123	112	11	0	0.2690	0.6037
					ApoA1-G75A(rs1799837)	33	22	11		120	86	34		–	–
Wang XY, [31] 2008, China	2003.10–2005.9	5	41.6 ± 10.3/40.7 ± 14.7	98/48	ApoA1-G75A(rs1799837)	143	70	20	53	92	45	28	19	10.447	0.0012
					ApoB-EcoR I(rs1042031)	143	125	18	0	92	82	10	0	0.304	0.5815
					ApoB-Xba I(rs693)	143	126	17	0	92	87	5	0	0.072	0.7888
					ApoB-3′-VNTR	142	109	33	0	92	73	18	1	0.009	0.9247
Zeng P, [19] 2014, China	2010.1–2013.12	5	39.85 ± 10.07/41.04 ± 13.61	53/38	ApoB-EcoR I(rs1042031)	108	95	13	0	98	96	2	0	0.010	0.9187
					ApoB-Xba I(rs693)	108	89	19	0	98	92	6	0	0.098	0.7546
Wei XD, [30] 2015, China	2011.1–2012.12	6	39 ± 10/41 ± 14	28/14	ApoA1-G75A(rs1799837)	45	32	13	0	30	28	2	0	0.036	0.8502
					ApoB-Xba I(rs693)	45	41	4	0	30	26	4	0	0.153	0.6956
					ApoB-EcoR I(rs1042031)	45	31	14	0	30	27	3	0	0.083	0.7731
Wei BF, [28] 2011, China	2007.1–2009.12	5	35.17 ± 11.73/34.76 ± 11.94	27/30	ApoB-C7623T	63	57	6	0	71	71	0	0	–	1.000
					ApoB-G12619A	63	56	7	0	71	69	2	0	0.014	0.9042

SNP Single Nucleotide Polymorphism, Χ^2* likelihood-ratio Χ², WH Wild homozygote, HT Heterozygote, MH mutational homozygote, NOS Newcastle-Ottawa Scale, N The total number of including, ONFH Osteonecrosis of the Femeral Head, HWE Hardy-Weinberg equilibrium tests