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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Reproduction. 2018 Jun 15;156(3):231–238. doi: 10.1530/REP-18-0111

Figure 2. Cellular expression of NLRP3 in human and mouse testes.

Figure 2

(A) In human (h), mouse (m), marmoset monkey (cj) and rhesus macaque (rh) NLRP3 transcripts indicated expression in whole testis lysates. (B) NLRP3 transcripts were detected in cultured human testicular peritubular cells (HTPCs; n = 2). Samples stem from men exhibiting normal spermatogenesis. Inflammasome-associated gene expression of ASC, CASP1 and IL1B was identified in HTPCs as well. (C) Mouse Sertoli cell line TM4 exhibited expression of Nlrp3, Pycard, Casp1 and Il1b transcripts. Negative controls consisted of non-reverse transcribed RNA as template (-RT) and a non-template reaction (–). Labels indicate amplicon lengths.