Table 1.
Characteristics of the study population (N=168)
| Variables* |
Frequency or median |
% or (min, max) |
|
|---|---|---|---|
|
| |||
| Baseline | Age (years) | 57 | (45, 78) |
|
| |||
| BMI (kg/m2) | 28.9 | (15.9, 54.2) | |
|
| |||
| CCL2 at baseline (pg/ml) | 291.71 | (21.04, 2192.27) | |
|
| |||
| Women | 105 | 62.5 | |
|
| |||
| Caucasian | 98 | 58.3 | |
|
| |||
| Follow-up | Knee rOA | 74 | 44.9 |
|
| |||
| Knee Sx | 91 | 54.2 | |
|
| |||
| Knee Sx Severity | |||
| None | 77 | 45.8 | |
| Mild | 40 | 23.8 | |
| Moderate/Severe | 51 | 30.4 | |
|
| |||
| WOMAC pain score | |||
| >=3 | 93 | 55.7 | |
| <3 | 75 | 44.3 | |
|
| |||
| Knee SxOA** | 59 | 35.8 | |
|
| |||
| Knee rOA progression | 81 | 50.6 | |
|
| |||
| Knee Osteophytes Medial (Tibial, Femoral) | 92 | 63.5 | |
|
| |||
| Knee Osteophytes progression Medial (Tibial, Femoral) | 54 | 37.5 | |
|
| |||
| Knee JSN Medial | 72 | 50.0 | |
|
| |||
| Knee JSN progression Medial | 53 | 37.1 | |
*
Some variables have missing values: Knee rOA, N=165; Knee Osteophytes, N=145; Knee JSN, N=144.
**
Knee SxOA requires at least one knee to have evidence of both knee rOA and knee Sx (symptoms). Knee K/L grades at the follow-up: K/L=0 (n=48, 29.1%), K/L=1 (n=43, 26.0%), K/L=2 (n=27, 16.4%), K/L=3 (n=28, 17.0%), K/L=4 (n=19, 11.5%).