Table 2.
Neuropsychological test scores at baseline in patients with and without apathy
| Total sample | AD | DLB | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Nonapathy (n = 124) |
Apathy (n = 72) |
p Value* | Nonapathy (n = 85) |
Apathy (n = 35) |
p value* | Nonapathy (n = 39) |
Apathy (n = 37) |
p Value* | |
| MMSE total (SD) | 23.6 (2.6) | 23.4 (2.8) | .415 | 23.7 (2.5) | 23.6 (2.2) | .486 | 23.4 (3.0) | 23.11(3.3) | .736 |
| MMSE pentagon, correct copy (%) | 61.8 | 51.4 | .102 | 70.9 | 61.8 | .340 | 48.4 | 45.5 | .814 |
| MMSE subtraction/word (SD) | 3.7 (1.4) | 3.6 (1.6) | .973 | 4.0 (1.3) | 4.0 (1.4) | .593 | 3.2 (1.5) | 3.3 (1.8) | .862 |
| MMSE memory (SD) | 1.0 (1.0) | 1.0 (1.0) | .886 | 0.8 (0.9) | 0.6 (0.8) | .462 | 1.4 (0.9) | 1.4 (1.1) | .870 |
| CVLT-II List A total (SD) | 20.4 (7.5) | 18.8 (9.2) | .092 | 18.5 (6.4) | 18.6 (7.7) | .695 | 24.5 (8.3) | 19.1 (10.5) | .020 |
| CVLT-II delayed recall (SD) | 1.9 (2.4) | 1.6 (2.2) | .416 | 1.4 (1.9) | 1.2 (2.1) | .496 | 3.1 (2.8) | 2.1 (2.3) | .141 |
| VOSP silhouettes (SD) | 13.7 (5.0) | 12.9 (5.2) | .269 | 13.8 (5.2) | 13.0 (6.2) | .480 | 13.7 (4.6) | 12.8 (4.2) | .084 |
| VOSP cubes (SD) | 6.4 (3.1) | 6.5 (3.0) | .885 | 7.2 (2.3) | 7.4 (2.3) | .711 | 5.2 (3.7) | 5.6 (3.5) | .652 |
| BNT (SD) | 10.1 (2.9) | 10.8 (2.9) | .165 | 10.1 (3.1) | 10.4 (3.2) | .644 | 10.1 (2.4) | 11.1 (2.5) | .146 |
| Stroop word (SD) | 69.4 (22.9) | 62.6 (20.6) | .087 | 75.9 (22.2) | 70.3 (18.3) | .260 | 55.1 (17.4) | 54.4 (20.1) | .111 |
| Stroop color (SD) | 44.0 (15.6) | 38.5 (14.5) | .021 | 47.4 (15.6) | 43.0 (11.6) | .148 | 36.3 (12.5) | 33.7 (15.9) | .302 |
| Stroop color-word (SD) | 16.2 (0.9) | 13.4 (8.3) | .133 | 18.3 (11.5) | 13.9 (8.9) | .103 | 11.5 (7.3) | 13.0 (7.7) | .405 |
| COWAT animals (SD) | 12.2 (4.4) | 10.7 (4.4) | .014 | 12.3 (4.2) | 11.2 (4.4) | .146 | 12.0 (4.7) | 10.3 (4.4) | .108 |
| Trail Making Test A (SD) | 111.0 (69.0) | 124.2 (92.1) | .686 | 96.8 (63.7) | 113.4 (82.1) | .544 | 143.1 (70.3) | 136.1 (101.9) | .173 |
| Memory domain, z-scores (SD) | 0.03 (0.8) | −0.04 (0.9) | .395 | −0.17 (0.87) | −0.25 (0.8) | .422 | 0.48 (0.8) | 0.15 (0.9) | .152 |
| Visuospatial domain, z-scores (SD) | 0.06 (0.7) | −0.09 (0.7) | .132 | 0.17 (0.7) | 0.06 (0.8) | .406 | −0.17 (0.8) | −0.22 (0.69) | .652 |
| Executive domain, z-scores (SD) | 0.08 (0.7) | −0.18 (0.8) | .014 | 0.30 (0.6) | 0.05 (0.6) | .104 | −0.30 (0.6) | −0.39 (0.8) | .823 |
Abbreviations: AD Alzheimer’s disease, BNT Boston Naming Test, COWAT Controlled Oral Word Association Test, CVLT-II California Verbal Learning Test, Second Edition, DLB Dementia with Lewy bodies, MMSE Mini Mental State Examination, VOSP Visual Object and Space Perception Battery
*Differences were analyzed using the Mann-Whitney U test and Pearson’s chi-square test