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Percentage of propranolol recovered in the skin (epidermis plus dermis) after 4 h of contact. White bars refer to intact skin; grey bars to stripped skin. Mean values±sd. Statistical differences with cream1: ∗ p<0.05; ∗∗ p<0.01. The difference between intact and stripped skin was significant for ointment1 (p<0.01) and for the gel (p<0.05).
