Table 1. Risk factor analysis for extrapulmonary vs. pulmonary NTM infection.
| Risk factors | Disease types | Crude analysis | Adjusted analysis | |||||
|---|---|---|---|---|---|---|---|---|
| Pulmonary (n = 36) | Extra pulmonary (n = 114) | Crude OR | 95% Cl | p-Value | Adjusted OR | 95% Cl | p-Value | |
| Age | ||||||||
| ≥50 | 25 (69.44) | 57 (50) | 0.44 | 0.198–0.978 | 0.041 | 0.75 | 0.171–3.295 | 0.703 |
| <50 | 11 (30.56) | 57 (50) | 1 | |||||
| Gender | ||||||||
| Male | 16 (44.44) | 53 (46.49) | 1.086 | 0.511–2.307 | 0.83 | 1.436 | 0.61–3.385 | 0.408 |
| Female | 20 (55.56) | 61 (53.51) | 1 | |||||
| BMIa | ||||||||
| <25 | 25 (89.29) | 66 (78.57) | 0.44 | 0.119–1.624 | 0.208 | 0.286 | 0.067–1.217 | 0.09 |
| ≥25 | 3 (10.71) | 18 (21.43) | 1 | |||||
| Anti-IFN-γ | ||||||||
| Yes | 1 (2.78) | 54 (47.37) | 31.5 | 4.172–237.809 | <0.001 | 20.749 | 2.704–159.235 | 0.004 |
| No | 35 (97.22) | 62 (54.39) | 1 | |||||
| HIV | ||||||||
| Yes | 3 (8.33) | 14 (12.28) | 1.54 | 0.417–5.694 | 0.764 | 1.59 | 0.37–6.837 | 0.533 |
| No | 33 (91.67) | 100 (87.72) | 1 | |||||
| Cutaneous lesionsb | ||||||||
| Yes | 0 (0) | 25 (21.93) | NA | NA | 0.002 | NA | NA | 0.998 |
| No | 36 (100) | 89 (78.07) | 1 | |||||
| Kidney disease | ||||||||
| Yes | 2 (5.56) | 21 (18.42) | 3.839 | 0.854–17.249 | 0.062 | 4.729 | 0.973–22.987 | 0.054 |
| No | 34 (94.44) | 93 (81.58) | 1 | |||||
| Cancer | ||||||||
| Yes | 2 (5.56) | 16 (14.04) | 2.776 | 0.607–12.701 | 0.243 | 1.888 | 0.355–10.058 | 0.456 |
| No | 34 (94.44) | 98 (85.96) | 1 | |||||
Notes:
p-Value with bold fonts refer to statistically significant p-value.
a
Some data were missing.
b
Cutaneous lesions comprised of Sweet’s disease, eczema and erythema nodusum. Adjusted analysis was adjusted with the three most significant factors (anti-IFN-γ, cutaneous lesions and age). Odds ratios (ORs) compared extrapulmonary infections (numerator) to pulmonary infections (denominator).