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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: J Hepatol. 2018 May 24;69(3):676–686. doi: 10.1016/j.jhep.2018.05.018

Fig. 7. Genetic disruption of the CCR2/CCL2 axis attenuates biliary injury.

Fig. 7

(A) Liver sections of saline- or BV6-injected wild-type and Ccr2−/− mice at day 5 (20×). Arrows: bile ducts. pv: portal vein. (B) Liver hydroxyproline content. (C) ALT, total BA and total bilirubin. (D) Macrophage infiltration markers and fibrosis markers by gene expression in whole livers. Wild-type: saline (n=8), BV6 (n=8); Ccr2−/−: saline (n=4), BV6 (n=5). *p<0.05, **p<0.005 (Mann-Whitney).