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Activation of platelets and coagulation pathway at disrupted atherosclerotic plaque
ADAMTS-13, a disintegrin and metalloprotease with a thrombospondin type 1 motif 13; ADP, adenosine diphosphate; CLEC-2, c-type lectin-like receptor 2; CRP, c-reactive protein; E-NTPDase, ecto-nucleoside triphosphate diphosphohydrolase; Mac, macrophage; SMC, smooth muscle cell; TF, tissue factor; TXA2, thromboxane A2; VWF, von Willebrand factor.
