Table 4. Baseline demographic and clinical characteristics after propensity score matching.
| Variable, n (%) | Clopidogrel | Prasugrel/Ticagrelor | p |
|---|---|---|---|
| (n = 268) | (n = 268) | ||
| Clinical presentation, n (%) | |||
| STEMI, n (%) | 137 (51.1) | 166 (61.9) | 0.01 |
| NSTEMI, n (%) | 110 (41) | 88 (32.8) | 0.06 |
| Unstable angina, n (%) | 20 (7.5) | 13 (4.8) | 0.28 |
| Symptom, n (%) | |||
| Killip ≥ 2 | 17 (6.4) | 25 (9.3) | 0.26 |
| Prior angina | 68 (31.3) | 94 (35.1) | 0.44 |
| Demographic, n (%) | |||
| Age (year) | 61 +/− 12 (31–89) | 58 +/− 11 (31–88) | 0.001 |
| Sex | |||
| Male | 223 (83.2) | 226 (84.3) | 0.81 |
| Female | 45 (16.8) | 42 (15.7) | 0.81 |
| Risk factors/past medical history, n (%) | |||
| Current smoking | 135 (50.4) | 135 (50.4) | 1 |
| Hypertension | 136 (50.8) | 130 (48.5) | 0.67 |
| Diabetes mellitus | 61 (22.8) | 66 (24.6) | 0.33 |
| Obesity (BMI > 30 Kg/m2) | 27 +/− 4.7 (18.5–44.8) | 27 +/− 4.9 (17–54) | 0.74 |
| Hyperlipidemia | 135 (50.4) | 121 (45.1) | 0.26 |
| Family history of coronary artery disease (CAD) | 52 (19.4) | 67 (25) | 0.15 |
| Prior STEMI | 37 (13.9) | 34 (12.7) | 0.70 |
| Prior NSTEMI | 14 (5.3) | 21 (7.9) | 0.29 |
| Prior angioplasty | 46 (17.2) | 40 (14.9) | 0.48 |
| Prior CABG | 9 (3.4) | 7 (2.6) | 0.80 |
| Prior Stroke | 13 (4.8) | 7 (2.6) | 0.25 |
| Peripheral vascular disease | 15 (5.6) | 12 (4.5) | 0.69 |
| Chronic Kidney Disease | 9 (3.4) | 12 (4.5) | 0.66 |
| Echographic characteristics, | |||
| Left Ventricular Ejection Fraction (%) | 55 +/− 11.3 (25–76) | 55 +/− 10.7 (20–80) | 0.30 |
| Treatment, n (%) | |||
| ACE inhibitors | 245 (93.9) | 247 (92.2) | 0.50 |
| Beta–blockers | 250 (95.4) | 259 (96.6) | 0.51 |
| Statins | 254 (97) | 262 (97.8) | 0.60 |
| Oral anticoagulants (VKA antagonists) | 32 (12.3) | 0 (0.0) | 0.0001 |
| GPIIbIIIa antagonist | 88 (33.7) | 83 (31) | 0.52 |
Values are n +/− median (range) or n (%)
ACE = angiotensin-converting enzyme; BMI = body mass index; CABG = coronary artery bypass graft surgery; NSTEMI = Non ST segment elevation myocardial infarction; STEMI = ST segment elevation myocardial infarction