Table 9. Univariate and multivariate analyses to predict MACE.
Variable | Univariate Analysis |
Multivariate Analysis |
||
---|---|---|---|---|
HR [95% CI] | P value | HR [95%CI] | P value | |
Age | 1.022 [1.000–1.046] | 0.051 | 1.003 [0.977–1.030] | 0.814 |
Sex | 1.456 [0.786–2.698] | 0.232 | ||
STEMI | 0,542 [0.296–0.995] | 0.048 | ||
NSTEMI | 2.011 [1.122–3.604] | 0,019 | 1.742 [0.844–3.592] | 0.133 |
Unstable angina | 0,813 [0,292–2.269] | 0,693 | ||
BMI | 1.012 [0,952–1.075] | 0,710 | ||
Smoking | 0.645 [0.351–1.182] | 0.156 | ||
Diabetes mellitus | 2.290 [1.278–4.102] | 0.005 | 0.959 [0.455–2.023] | 0.913 |
Hypertension | 1.536 [0.837–2.818] | 0.166 | ||
Dyslipidemia | 1.530 [0.846–2.765] | 0.160 | ||
Prior PCI | 0.954 [0.460–1.977] | 0.899 | ||
CKD | 3.594 [1.675–7.711] | 0.001 | 1.726 [0.641–4.645] | 0.280 |
History of stroke | 3.065 [1.298–7.238] | 0.011 | 1.447 [0.503–4.162] | 0.493 |
Peripheral vascular disease | 2.566 [1.238–5.318] | 0,011 | 1.865 [0.807–4.311] | 0.145 |
Killip 2 to 4 | 2.295 [1.108–4.757] | 0.025 | 1.940 [0.368–2.400] | 0.897 |
Creatinine | 1.003 [0.999–1.008] | 0.180 | ||
HbA1c | 1.207 [1.025–1.422] | 0.024 | ||
BNP at admission | 1.000 [1.000–1.001] | 0.020 | ||
CRP at admission | 1.011 [1.005–1.017] | 0.001 | 1.011 [1.004–1.018] | 0.003 |
Troponin at admission | 1.006 [1.002–1.011] | 0,005 | 1.008 [1.002–1.015] | 0.015 |
Left ventricular ejection fraction | 0.970 [0.947–0.993] | 0.011 | ||
Clopidogrel | 1.741 [0.884–3.429] | 0.109 | ||
ACE-inhibitor | 0.320 [0.149–0.686] | 0,003 | ||
Statin | 0.274 [0.098–0.765] | 0,013 | ||
Stent's total length | 1.016 [1.005–1.026] | 0,003 | 1.006 [0.990–1.022] | 0.487 |
Stent's Diameter | 0.955 [0.608–1.500] | 0.843 | ||
DES | 1.865 [0.946–3.678] | 0.072 | ||
Three-vessel disease | 1.816 [1.004–3.284] | 0.048 | 1.532 [0.757–3.101] | 0.236 |
Left main coronary artery | 1.770 [0.635–4.937] | 0.275 | ||
Bifurcation | 1.744 [0.689–4.415] | 0.240 | ||
Hemorrhagic event | 4.952 [1.938–12.656] | 0.001 | 3.119 [1.020–9.533] | 0.046 |
HR = Hazard ratio; CI = confidence interval
ACE = angiotensin-converting enzyme; BMI = body mass index; BNP = brain natriuretic peptide; CRP = C-reactive protein; DES = drug eluting stent; NSTEMI = Non ST segment elevation myocardial infarction; STEMI = ST segment elevation myocardial infarction