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Bioavailability parameters of unconjugated epigallocatechingallate (EGCG) after oral administration of nanoEGCG.
| Bioavailability parameters | Plasma | Brain | ||
|---|---|---|---|---|
| Free EGCG | NanoEGCG | Free EGCG | Nano EGCG | |
| Tmax | 3 h | 4 h | 2 h | 3 h |
| Cmax | 240.10 ± 15.3 μg/ml | 334.65 ± 6.85 μg/ml | 12.90 ± 0.7 μg/ml | 20.33 ± 0.75 μg/ml |
| AUC0-∞ | 1103.29 ± 136.7 mg.h/L | 2520.80 ± 66.7 mg.h/L | 51.92 ± 5.7 mg.h/L | 120.32 ± 7.5 mg.h/L |
