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Specific activities of individual CYP enzymes (pmol product/nmolP450/min)
| Sample | CYP3A | CYP2A | CYP2C |
| Liver microsomal fraction | 2193 ± 523 | 210 ± 70 | 136 ± 31 |
| CYP – containing fractions | 3716 ± 428 | 423 ± 148 | n.d. |
The nifedipine oxidase (CYP3A), coumarin 7-hydroxylation (CYP2A) and tolbutamide methyl-hydroxylation activities in microsomes and fractions containing partially purified CYP enzymes were determined as indicated in Materials and Methods, n.d., not determined.
