Table 4.
Relaxivities (r1p) determined for selected Mn(II) complexes (at 0.5 T field strength, 25 °C and pH = 7.4).
| Chelate | r1p (mM−1s−1) | Chelate | r1p (mM−1s−1) |
|---|---|---|---|
| [Mn(PCTA)]− | 1.50 | [Mn(DOTP)]6− | 2.37[e] |
| [Mn(PC3AMH)]2+ | 1.21 | [Mn(DOTAM)]2+ | 1.11, 0.96[f] |
| [Mn(PC3AMGly)]− | 1.44 | [Mn(DOTMA)]2−/[Mn(H2DOTMA)] (q = 0) | 1.76/2.98[g] |
| [Mn(PC3AMPip)]2+ | 1.28 | [Mn(DOTA)]2−/[Mn(H2DOTA)] (q = 0) | 1.25/3.20[f] |
| [Mn(DO3A)]− | 1.18-1.31, 1.30[a] | [Mn(trans-DO2A)] | 1.50[a] |
| [Mn(DO3AMH)]2+ | 1.33 | [Mn(cis-DO2A)] | 2.10[a] |
| [Mn(DO3P)]4− | 2.23[b] | [Mn(cis-DO2AMMe2)]2+ | 2.50[h] |
| [Mn(ODO3A)]− | 1.40 | [Mn(cis-BzDO2AMH)]2+ | 3.80[i] |
| [Mn(AAZTA)]2−, [c] | 1.60[d] | [Mn(cis-DO2AMBz2)]2+ | 3.50[i] |
[a]
Rolla et al. (2013);
[b]
determined in the pH range of 8.5–9.3 where mainly the [Mn(DO3P)]4− complex exists in solution;
[c]
AAZTA = 6-amino-6-methylperhydro-1,4-diazepine tetraacetic acid;
[d]
Tei et al. (2011);
[e]
determined in the pH range of 10.0–11.0 where the deprotoanted complex exists in solution;
[f]
Wang and Westmoreland (2009) measured at 0.5 T field strength and 37 °C;
[g]
Tircsó and Woods (in preparation);
h
Forgács et al. (2016);
[i]
Forgács et al. (2017).