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. 2018 Aug 13;9:885. doi: 10.3389/fphar.2018.00885

Table 3.

Effect of 1 and 3 on selected types of VGCCs and potassium channels.

Compound Cav1.2a (L-type) Cav2.1a (P/Q-type) Cav3.1a (T-type) BKb channel Kv1.1b Kv2.1b Kv3.1b
1 10.1 ± 1.2% 1.3 ± 0.3% 11.8 ± 2.9% 15.5 ± 1.0% 2.8 ± 1.1% 1.0 ± 1.1% 0.5 ± 0.5%
3 13.5 ± 4.1% 7.8 ± 1.2% 20.4 ± 7.4% 6.7 ± 7.7%

aPeak current inhibition ratio of compounds at 10 μM; bPeak current inhibition ratio of compounds at 30 μM; “-” not tested, due to the limited amount of material. Data represent the mean ± SEM of 3 or 4 cells.