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. 2017 Dec 8;104(2):374–383. doi: 10.1002/cpt.940

Figure 3.

Figure 3

Sensitivity analysis of varying stomach pH on ribociclib absorption in PBPK models. Simulations were performed using qualified models with (a) Simcyp ADAM model and (b) GastroPlus ACAT model with dissolution data from varying pH levels.