Table 2.
PCA results [Color table can be viewed at http://wileyonlinelibrary.com]
| PC1 | PC2 | PC3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| FA | AD | RD | FA | AD | RD | FA | AD | RD | ||
| M1‐Motor Thalamus | L | 0.4944 | 0.71558 | 0.67955 | 0.70197 | |||||
| R | 0.43883 | 0.67178 | 0.64759 | 0.71228 | ||||||
| M1‐Putamen | L | 0.59931 | 0.77047 | 0.78749 | 0.61072 | |||||
| R | 0.5695 | 0.66923 | 0.77874 | 0.66393 | ||||||
| PMC‐Motor Thalamus | L | 0.43661 | 0.61912 | 0.73059 | 0.71341 | |||||
| R | 0.45098 | 0.64774 | 0.68891 | 0.68221 | ||||||
| PMC‐Putamen | L | 0.63268 | 0.74575 | 0.79596 | 0.58385 | −0.43091 | ||||
| R | 0.59244 | 0.67459 | 0.77046 | 0.55995 | −0.46135 | |||||
| S1‐Somatosensory Thalamus | L | 0.51495 | 0.72899 | 0.70752 | 0.68283 | |||||
| R | 0.46951 | 0.66197 | 0.61133 | 0.70453 | −0.43991 | 0.46866 | ||||
| S1‐Putamen | L | 0.59981 | 0.77641 | 0.77865 | 0.61116 | |||||
| R | 0.62317 | 0.76785 | 0.75927 | 0.60292 | ||||||
| DLPFC‐Prefrontal Thalamus | L | 0.69285 | 0.65991 | −0.67064 | ||||||
| R | 0.6591 | 0.74847 | −0.74165 | |||||||
| DLPFC‐Caudate | L | 0.68251 | 0.68763 | 0.48431 | ||||||
| R | 0.66408 | 0.69064 | 0.47344 | 0.59726 | −0.42632 | |||||
| PPC ‐ Parietal Thalamus | L | −0.57012 | 0.6499 | 0.83471 | ||||||
| R | −0.54872 | 0.55881 | 0.75936 | 0.41155 | ||||||
| Uncinate Fasciculus | L | −0.4484 | 0.43608 | 0.61483 | ||||||
| R | 0.50387 | 0.50397 | ||||||||
| Mid Cingulum | L | −0.54713 | 0.47198 | 0.71255 | 0.4385 | |||||
| R | −0.50473 | 0.56258 | 0.77297 | 0.40841 | 0.4084 | |||||
| Posterior Cingulum | L | −0.5396 | 0.76733 | 0.42102 | 0.44304 | |||||
| R | −0.53816 | 0.76758 | 0.4282 | 0.41278 | ||||||
| V1 ‐ Visual Thalamus | L | −0.52886 | 0.44216 | 0.74869 | ||||||
| R | −0.53247 | 0.65093 | 0.44095 | |||||||
| IFOF | L | −0.65731 | 0.5482 | 0.84464 | ||||||
| R | −0.60571 | 0.49602 | 0.81886 | |||||||
| ILF | L | −0.63733 | 0.50695 | 0.77461 | ||||||
| R | −0.61165 | 0.47702 | 0.79844 | |||||||
| Mid Corpus Callosum | −0.67649 | 0.57568 | 0.84759 | 0.41806 | ||||||
| Posterior Corpus Callosum | −0.6755 | 0.61222 | 0.82682 | |||||||
Correlation co‐efficients for each PC showing the contribution of each measure of diffusivity to each PC for all tracts; for visualization purposes, these have only been shown for co‐efficients that are smaller than or greater than 0.4. Tracts are color‐coded according to the network to which they putatively belong. Blue: Sensorimotor Network tracts; Green: Cognitive network tracts; Pink: Limbic network tracts; Orange: Visual network tracts; Purple: Control (non‐HD phenotype); Brown: Interhemispheric tracts. AD: axial diffusivity; DLPFC: dorsolateral prefrontal cortex; FA: fractional anisotropy; IFOF: inferior fronto‐occipital Fasciculus; ILF: inferior lateral Fasciculus; M1: primary motor cortex; PMC: premotor cortex; PPC: posterior parietal cortex; RD: radial diffusivity; S1: primary somatosensory cortex; V1: primary visual cortex.