Table 1.
Enzyme performance requirements.12
| Industry segment | Product price range [€ kgprod. −1] |
Allowable cost contribution of the catalyst [€ kgprod. −1] |
Minimal productivity [kgProd. kgcat. −1][a] |
Minimal productivity [TN][b] |
|---|---|---|---|---|
| pharma | >100 | 10 | 20 | 4000 |
| fine chemicals | >15 | 1.5 | 133 | 26 666 |
| speciality chemicals | 5 | 0.25 | 800 | 16 0000 |
| bulk chemicals | 1 | 0.05 | 4000 | 80 0000 |
[a] Assuming an average catalyst cost of 200 € kg−1 (for crude enzyme preparations). [b] Assuming an enzyme molecular weight of 40 kDa and a product molecular weight of 200 g mol−1. TN=mol(product)×mol(enzyme)−1.