Table 3.

FAM19A4/mir124‐2 methylation findings over time

Patient ID	Histotype	Baseline		Follow‐up 6 months		Follow‐up 18 months		Second round
		Cyto	Meth	Cyto	Meth	Cyto	Meth	Cyto	Meth	Cancer detected in round
Case 1	SCC	Normal	Pos	BMD	Pos	BMD	Pos			1
Case 2	AC	BMD	Pos	BMD	Pos					1
Case 3	SCC	BMD	Pos	BMD	Pos	>BMD	Pos			1
Case 4	AC	BMD	Pos	>BMD	Pos					1
Case 5	SCC	BMD	Pos	>BMD	Pos					1
Case 6	SCC	BMD	Pos	>BMD	Pos					1
Case 7	SCC	>BMD	Pos	>BMD	Pos					1
Case 8	SCC	Normal	Pos			>BMD*	Pos			1
Case 9	AC	BMD	Pos			>BMD	Pos			1
Case 10	AC	Normal	Neg					Normal	Pos	2
Case 11	SCC	Normal	Neg					BMD	Pos	2
Case 12	AC	Normal	Pos					>BMD	Pos	2
Case 13	SCC	Normal	Pos					>BMD	Pos	2
Case 14	SCC	>BMD	Pos					>BMD	Pos	2
Case 15	AC	Normal	Neg					BMD	Pos	3
Case 16	SCC	Normal	Neg					Normal	Neg	3
Case 17	SCC	Normal	Pos					Normal	Pos	3
Case 18	SCC	>BMD	Pos					Normal	Pos	3

Methylation and cytology results of scrapes collected at baseline and follow‐up (i.e., 6 months, 18 months and/or second screening round) of women diagnosed with cervical cancer, ranked by screening round wherein the cancer was diagnosed (last column).

Follow‐up at 36 months instead of 18 months.

Abbreviations: AC = adenocarcinoma; BMD = borderline or mild dyskaryosis; cyto = cytology; meth = methylation; SCC= squamous cell carcinoma.