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. 2018 Jun 25;70(9):1228–1241. doi: 10.1111/jphp.12950

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© 2018 The Authors. Journal of Pharmacy and Pharmacology published by John Wiley & Sons Ltd on behalf of Royal Pharmaceutical Society

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Restoration of attenuated movement in ischemic stroke following mesenchymal stem cells transplantation with Salvia miltiorrhiza Bunge (a) The percentage use of the affected (left), unaffected (right) and simultaneous limb was tested using cylinder test in the different treatment groups: Sham operation; control; S. miltiorrhiza Bunge only; mesenchymal stem cell only; mesenchymal stem cell treatment with S. miltiorrhiza Bunge. Treatment of mesenchymal stem cell with S. miltiorrhiza Bunge is the most effective method, showing the restoration of the percentage use of the affected limb. (b) The immobility time of animals in the group of treatment of mesenchymal stem cell with S. miltiorrhiza Bunge was reduced in a significant manner compared to other groups. Columns, mean; bars, SE. ##: P < 0.01, compared with the values of the sham operation group; **: P < 0.01, compared with the values of the control group.