Table 4.
Univariable logistic regression analyses of factors influencing outcomes
|
Any complication (n = 35 reconstructions) |
Any reoperation (n = 29 reconstructions) |
Any removal of ADM and/ or implant (n = 24 reconstructions) |
|||||
|---|---|---|---|---|---|---|---|
| Factor | Odds ratio | P | Odds ratio | P | Odds ratio | P | |
| Age (years) |
1·0 (0·96, 1·05) |
0·773 |
1·03 (0·99, 1·09) |
0·145 |
1·04 (0·99, 1·01) |
0·151 | |
| BMI (kg/m2) |
1·08 (0·91, 1·28) |
0·371 |
1·00 (0·84, 1·19) |
0·999 |
1·06 (0·89, 1·28) |
0·501 | |
| Smoking |
0·89 (0·30, 2·65) |
0·832 |
0·64 (0·19, 2·23) |
0·488 |
0·68 (0·16, 2·84) |
0·593 | |
| Diabetes mellitus |
2·26 (0·12, 38·64) |
0·573 |
3·06 (0·18, 52·48) |
0·441 |
3·63 (0·21, 62·96) |
0·376 | |
| Previous breast surgery |
1·06 (0·78, 1·42) |
0·711 | –* | –* | |||
| Chemotherapy | |||||||
| Preoperative |
0·70 (0·20, 2·36) |
0·560 |
0·67 (0·16, 2·81) |
0·585 |
0·86 (0·21, 3·55) |
0·839 | |
| Postoperative |
2·03 (0·63, 6·56) |
0·235 |
2·27 (0·69, 7·47) |
0·177 |
1·65 (0·47, 5·91) |
0·435 | |
| Adjuvant radiotherapy |
7·23 (0·75, 69·95) |
0·087 |
3·61 (0·55, 23·77) |
0·181 |
5·12 (0·76, 34·44) |
0·093 | |
| Hormone therapy |
1·46 (0·54, 3·99) |
0·457 |
0·84 (0·27, 2·62) |
0·769 |
0·88 (0·26, 2·98) |
0·834 | |
| Targeted therapy | –† | –† | –† | ||||
| Incision technique | 0·152 | ||||||
| IMF |
1·00 (reference) |
1·00 (reference) |
1·00 (reference) |
||||
| Other‡ |
1·40 (0·49, 3·99) |
0·527 |
3·56 (0·79, 15·95) |
0·097 |
8·75 (0·45, 170·96) |
||
| Nipple‐sparing mastectomy | |||||||
| Yes |
1·00 (reference) |
1·00 (reference) |
1·00 (reference) |
||||
| No |
0·56 (0·20, 1·55) |
0·266 |
0·63 (0·22, 1·84) |
0·400 |
0·55 (0·17, 1·80) |
0·332 | |
| Mastectomy weight (g)§ |
1·94 (1·33, 2·82) |
< 0·001 |
1·54 (1·09, 2·20) |
0·015 |
1·55 (1·11, 2·17) |
0·010 | |
| Mastectomy weight – implant weight (g)§ |
1·33 (0·92, 1·92) |
0·126 |
1·18 (0·82, 1·71) |
0·336 |
1·18 (0·80, 1·73) |
0·397 | |
Values in parentheses are 95 per cent confidence intervals. Ninety‐one breasts were included in the analyses.
*
None of the patients who had undergone breast surgery previously were reoperated.
†
All patients who underwent targeted therapy had complications, reoperations and implant removal.
‡
All incisions other than an incision in the inframammary fold (IMF).
§
Odds ratio calculated for a 100‐g weight difference. ADM, acellular dermal matrix.