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. 2018 Jul 4;57(32):10153–10157. doi: 10.1002/anie.201804831

Scheme 2.

Scheme 2

Reactions used for screening the nucleophile preference of the D6X/T26X library. Stereoselectivity was analyzed through cyclic acetal formation. Reaction conditions: i) NaBH4, MeOH ii) 2,2‐dimethoxypropane, H+.