Table 2.
Hypoglycaemia outcomes using variable (on‐treatment) follow‐up
| Hypoglycaemia | Inpatient/ED hypoglycaemia | |||||||
|---|---|---|---|---|---|---|---|---|
| Gla‐300 switchers(n = 1592) | IDeg switchers(n = 1592) | aHR/aRRa(95% CI) | P b | Gla‐300 switchers(n = 1592) | IDeg switchers(n = 1592) | aHR/aRRa(95% CI) | P b | |
| Patients with ≥1 event, n (%) | 148 (9.3) | 138 (8.7) | – | – | 26 (1.6) | 30 (1.9) | – | – |
| Follow‐up to first event, person‐years | 557 | 572 | – | – | 585 | 598 | – | – |
| Crude incidence rate, PPY | 0.27 | 0.24 | 1.02 (0.81–1.29) | .877 | 0.04 | 0.05 | 0.80 (0.47–1.36) | .417 |
| Events, n | 223 | 222 | – | – | 32 | 47 | – | – |
| Total follow‐up, person‐years | 589 | 603 | – | – | 589 | 603 | – | – |
| Event rate, PPY | 0.38 | 0.37 | 0.94 (0.78–1.14) | .558 | 0.05 | 0.08 | 0.56 (0.35–0.90) | .016 |
Abbreviations: aHR, hazard ratio adjusted for baseline hypoglycaemia incidence; aRR, rate ratio adjusted for baseline hypoglycaemia incidence; ED, emergency department; Gla‐300, insulin glargine 300 units/mL; IDeg, insulin degludec; PPY, per person‐year.
a
aHR for crude incidence rate (proportional hazard Cox model); aRR for event rate (Poisson regression).
b
P values adjusted for baseline hypoglycaemia incidence.