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. 2018 Aug;188(8):1807–1819. doi: 10.1016/j.ajpath.2018.05.004

Figure 6.

Figure 6

Ethanol (E) up-regulates hepatic Slu7 in mice and in patients with alcoholic steatohepatitis (ASH). A: Mice were pair fed either a control (Con) diet or an ethanol-containing diet for 10 days, followed by single gavage of ethanol. Western blot analysis of hepatic Slu7. B and C: Hepatic levels of SLU7 were determined in liver tissues from normal livers and patients with ASH. B: Relative hepatic mRNA levels of SLU7. C: Western blot analysis of hepatic SLU7. Data are expressed as means ± SEM (AC). n = 7 (normal liver); n = 5 (ASH); n = 4 to 6 mice (A). P < 0.05 versus pair-fed controls; †††P < 0.001 versus normal livers. GAPDH, glyceraldehyde-3-phosphate dehydrogenase.