Table 4.
Low stage (n = 572) | High stage (n = 821) | |||||||
---|---|---|---|---|---|---|---|---|
HR | Lower CI | Upper CI | p valuea | HR | Lower CI | Upper CI | p valuea | |
Model 1 | ||||||||
Smoking | <0.001 | |||||||
Former | 2.02 | 1.05 | 3.86 | 1.65 | 1.13 | 2.41 | ||
Current | 2.90 | 1.44 | 5.82 | 0.002 | 3.50 | 2.31 | 5.29 | |
Alcohol amount | 0.445 | |||||||
Moderate | 0.67 | 0.35 | 1.30 | 0.75 | 0.50 | 1.12 | ||
Hazardous/harmful | 1.45 | 0.90 | 2.34 | 0.074 | 1.08 | 0.78 | 1.50 | |
Model 2 | ||||||||
Smoking | 0.005 | |||||||
Former | 2.05 | 1.06 | 3.97 | 1.35 | 0.92 | 1.99 | ||
Current | 2.38 | 1.16 | 4.90 | 0.052 | 1.75 | 1.11 | 2.75 | |
Alcohol amount | 0.619 | |||||||
Moderate | 0.72 | 0.37 | 1.40 | 0.80 | 0.53 | 1.19 | ||
Hazardous/harmful | 1.50 | 0.92 | 2.45 | 0.121 | 1.05 | 0.76 | 1.45 | |
Model 3 | ||||||||
Smoking | 0.004 | |||||||
Former | 2.15 | 1.09 | 4 23 | 1.40 | 0.94 | 2.09 | ||
Current | 2.54 | 1.19 | 5.45 | 0.075 | 1.77 | 1.09 | 2.86 | |
Alcohol amount | 0.655 | |||||||
Moderate | 0.71 | 0.36 | 1.40 | 0.81 | 0.54 | 1.23 | ||
Hazardous/harmful | 1.58 | 0.96 | 2.60 | 0.086 | 1.04 | 0.75 | 1.46 | |
Model 4 | ||||||||
Smoking | 0.004 | |||||||
Former | 2.00 | 1.01 | 3.97 | 1.37 | 0.92 | 2.05 | ||
Current | 2.29 | 1.06 | 4.94 | 0.075 | 1.70 | 1.04 | 2.77 | |
Alcohol amount | 0.904 | |||||||
Moderate | 0.68 | 0.34 | 1.33 | 0.85 | 0.56 | 1.29 | ||
Hazardous/harmful | 1.44 | 0.88 | 2.36 | 0.135 | 1.02 | 0.73 | 1.42 |
Model 1 (minimally adjusted): adjusted for age and gender.
Model 2: additionally adjusted for clinical features (stage, treatment, comorbidity, BMI).
Model 3: additionally adjusted for social features (education, annual household income, IMD, marital status, ethnicity).
Model 4 (fully adjusted): additionally includes smoking or drinking.
HR = hazard ratio; CI = confidence interval.
p values for trend.