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. 2018 Jul 16;23(7):1737. doi: 10.3390/molecules23071737
API active pharmaceutical ingredient
I polymorphic form benzocaine subjected to ball milling
II polymorphic form benzocaine subjected to micro milling
III and IIIa polymorphic forms benzocaine in initial form and form subjected to cryogenic grinding
EXP excipient
DFT density functional theory
FT-IR Fourier transform infrared spectroscopy
HPLC-DAD high-performance liquid chromatography with diode array detector
RH relative humidity
T temperature
PAMPA parallel artificial membrane permeability assay
PXRD X-ray powder diffraction