API |
active pharmaceutical ingredient |
I polymorphic form |
benzocaine subjected to ball milling |
II polymorphic form |
benzocaine subjected to micro milling |
III and IIIa polymorphic forms |
benzocaine in initial form and form subjected to cryogenic grinding |
EXP |
excipient |
DFT |
density functional theory |
FT-IR |
Fourier transform infrared spectroscopy |
HPLC-DAD |
high-performance liquid chromatography with diode array detector |
RH |
relative humidity |
T |
temperature |
PAMPA |
parallel artificial membrane permeability assay |
PXRD |
X-ray powder diffraction |